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Northwestern Proteomics has a set of analyses that it considers "routine."  These services are available for rapid turnaround, but offer minimal customization. These are typically qualitative or semi-quantitative in nature.

Note: Prices listed here are estimates for budgetary purposes only, in most cases, prices are reduced when samples are submitted in bulk. To see approved pricing, click here. For more a more accurate quotation, please submit a collaboration request (at the bottom of this page) or contact Northwestern Proteomics at This email address is being protected from spambots. You need JavaScript enabled to view it..

Work performed in the proteomics core should be acknowledged as shown below:

"Proteomics services were performed by the Northwestern Proteomics Core Facility, generously supported by NCI CCSG P30 CA060553 awarded to the Robert H Lurie Comprehensive Cancer Center, instrumentation award (S10OD025194) from NIH Office of Director, and the National Resource for Translational and Developmental Proteomics supported by P41 GM108569"


Untargeted Quantitative Peptide Proteomics

Untargeted Quantitative Peptide Proteomics

Quantitation requires a consultation to help design the experiment. Depending on the problem, we can use a variety of methods to perform the analysis.

  • Metabolic Label: SILAC
  • Isobaric Label: iTraq/TMT
  • Label-Free Peptide Quantitation

Pricing

Northwestern/CBC: Contact us for a quote
LCC: Contact us for a quote
External Academic/Nonprofit: Contact us for a quote
External For-Profit Industry: Contact us for a quote

Instruments Used

Orbitrap Elite
Q Exactive HF

Protein Identification

Protein Identification

In this service line, proteins are identified after an in-gel or in-solution digestion.

Pricing

Northwestern/CBC: Starting at $202 (depending on number of samples submitted and length of LCMS gradient)
LCC: Starting at $184 (depending on number of samples submitted and length of LCMS gradient)
External Academic/Nonprofit: Starting at $303 (depending on number of samples submitted and length of LCMS gradient)
External For-Profit Industry: Starting at $505 (depending on number of samples submitted and length of LCMS gradient)

Instruments Used

Orbitrap Elite
Q Exactive HF

Top Down Mass Spectrometry

Top Down Mass Spectrometry

Top-down mass spectrometry is an emerging technology which strives to preserve the post-translationally modified forms of proteins present in vivo by measuring them intact, rather than measuring peptides produced from them by proteolysis.

Pricing

Northwestern/CBC: Starting at $202 (depending on number of samples submitted and length of LCMS gradient)
LCC: Starting at $184 (depending on number of samples submitted and length of LCMS gradient)
External Academic/Nonprofit: Starting at $303 (depending on number of samples submitted and length of LCMS gradient)
External For-Profit Industry: Starting at $505 (depending on number of samples submitted and length of LCMS gradient)

Instruments Used

Orbitrap Elite
Q Exactive HF
Q Exactive UHMR

IP-MS Pulldown

IP-MS Pulldown

Co-immunoprecipitation is an extension of IP that is based on the potential of IP reactions to capture and purify the primary target (i.e., the antigen) as well as other bound macromolecules.

Pricing

Northwestern/CBC: Starting at $202 (depending on number of samples submitted and length of LCMS gradient)
LCC: Starting at $184 (depending on number of samples submitted and length of LCMS gradient)
External Academic/Nonprofit: Starting at $303 (depending on number of samples submitted and length of LCMS gradient)
External For-Profit Industry: Starting at $505 (depending on number of samples submitted and length of LCMS gradient)

Instruments Used

Orbitrap Elite
Q Exactive HF

BioID

BioID

BioID is a service offered to collaborators who wish to identify the target of biotin ligase that has been tagged onto their protein via traditional cloning methods.

Pricing

Northwestern/CBC: Starting at $202 (depending on number of samples submitted and length of LCMS gradient)
LCC: Starting at $184 (depending on number of samples submitted and length of LCMS gradient)
External Academic/Nonprofit: Starting at $303 (depending on number of samples submitted and length of LCMS gradient)
External For-Profit Industry: Starting at $505 (depending on number of samples submitted and length of LCMS gradient)

Instruments Used

Orbitrap Elite
Q Exactive HF

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